2,2-二甲基-1-(4-甲基苯基)丙-1-酮合成路线 （共 30 条）
反应条件
1: 1,1,1,3,3,3-hexamethyl-disilazane / dichloromethane / -12 - 20 °C / Inert atmosphere 2: diethylzinc / dichloromethane / 16 h / 0 °C / Inert atmosphere 3: tetrabutyl ammonium fluoride; oxygen; palladium diacetate; potassium carbonate / toluene / 100 °C / 760.05 Torr View Scheme
参考文献
Chemical Communications, , vol. 48, # 13 p. 1922 - 1924
反应条件
aluminium trichloride T=0°C;
参考文献
Journal of the Chemical Society, , p. 1950,1953
反应条件
Friedel-Crafts method;
参考文献
Boyer, Bernard; Lamaty, Gerard; Pastor, Jean-Pierre; Roque, Jean-Pierre
Bulletin de la Societe Chimique de France, 1989 , # 4 p. 459 - 462
参考文献
Journal of Organometallic Chemistry, , vol. 127, p. 315 - 324
参考文献
Bulletin de la Societe Chimique de France, , p. 3609 - 3616
反应条件
(i), (ii) (oxidation); Multistep reaction;
参考文献
Bulletin de la Societe Chimique de France, , p. 167 - 172
反应条件
1: 56 percent / aq. KMnO4 / 4 h / Heating 2: 99 percent / SOCl2 / 1.5 h / Heating View Scheme
参考文献
Aicher, Thomas D.; Bebernitz, Gregory R.; Bell, Philip A.; Brand, Leonard J.; Dain, Jeremy G.; Deems, Rhonda; Fillers, William S.; Foley, James E.; Knorr, Douglas C.; Nadelson, Jeffrey; Otero, Dario A.; Simpson, Ronald; Strohschein, Robert J.; Young, Douglas A.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 1 p. 153 - 163
反应条件
1: 56 percent / aq. KMnO4 / 4 h / Heating 2: 93 percent / NaBH4 / ethanol / 6 h / 0 - 20 °C View Scheme
参考文献
Aicher, Thomas D.; Bebernitz, Gregory R.; Bell, Philip A.; Brand, Leonard J.; Dain, Jeremy G.; Deems, Rhonda; Fillers, William S.; Foley, James E.; Knorr, Douglas C.; Nadelson, Jeffrey; Otero, Dario A.; Simpson, Ronald; Strohschein, Robert J.; Young, Douglas A.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 1 p. 153 - 163
反应条件
tetraphosphorus decasulfide in pyridine
T=110°C; Cycloaddition; 24 h; Product distribution; Further Variations:time;
参考文献
Okuma; Shibata; Shioji; Yokomori
Chemical Communications, 2000 , # 16 p. 1535 - 1536
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane
24 h; Heating;
参考文献
Norris, Robert K.; Barker, Steven D.; Neta, P.
Journal of the American Chemical Society, 1984 , vol. 106, # 11 p. 3140 - 3144
