1-(3,4-二甲氧基苯基)-2,2-二甲基丙烷-1-酮合成路线 (共 6 条)
反应条件
bismuth trifluoromethanesulphonate T=80°C; Friedel-Crafts acylation; 0.5 h; Ionic liquid;
参考文献
Tran, Phuong Hoang; Duus, Fritz; Le, Thach Ngoc
Tetrahedron Letters, 2012 , vol. 53, # 2 p. 222 - 224
反应条件
oxygen; anhydrous cobalt diacetate; metachloroperbenzoic acid; N-hydroxy-4-methoxycarbonylphthalimide in 1,4-dioxane; ethyl acetate T=25°C; 24 h;
参考文献
Baiocco, Paola; Barreca, Anna Maria; Fabbrini, Maura; Galli, Carlo; Gentili, Patrizia
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 1 p. 191 - 197
反应条件
trifluorormethanesulfonic acid; titanium(IV) chloride tris(trifluoromethanesulfonate) in acetonitrile 12 h; Ambient temperature;
参考文献
Izumi, Jun; Mukaiyama, Teruaki
Chemistry Letters, 1996 , # 9 p. 739 - 740
反应条件
(i) NaNH2, toluene, (ii) /BRN= 969135/; Multistep reaction;
参考文献
Moffett,R.B. et al.
Journal of Medicinal Chemistry, 1964 , vol. 7, p. 178 - 186
参考文献
Tsatsas,G.; Cotakis,G.
Bulletin de la Societe Chimique de France, 1970 , p. 3609 - 3616
反应条件
pyridine hydrochloride
T=200 - 220°C;
参考文献
Moffett,R.B. et al.
Journal of Medicinal Chemistry, 1964 , vol. 7, p. 178 - 186