1-(嘧啶-2-基)哌啶-4-甲酸合成路线 （共 2 条）
反应条件
lithium hydroxide hydrate; water in tetrahydrofuran T=20°C; 18 h; Inert atmosphere;
参考文献
VANTIA LIMITED; BATT, Andrzej, Roman; HEENEY, Celine, Marguerite, Simone
Patent: WO2010/97576 A1, 2010 ;
Location in patent: Page/Page column 43-44 ;
WO 2010/097576 A1
反应条件
1: potassium carbonate / ethanol / |Reflux 2: sodium hydroxide / ethanol / |Reflux View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 21 p. 8696 - 8711
