暂无反应条件数据

1: 2-(2-tert-butoxycarbonylamino-pyridin-4-yl)-1-(3-methylphenyl)ethanone With bromine in acetic acid T=20°C; 0.5 h; 2: ethanethioamide in N,N-dimethyl-formamide T=20°C; 20 h; 3: With hydrogenchloride in water T=100°C; 1 h;

1: 86 percent / Br2; AcOH / 3 h / 80 °C 2: 63 percent / dimethylformamide / 14 h / 20 °C 3: 95 percent / NaOH / ethanol; H2O / 2 h / 20 °C 4: 72 percent / 0.25 h / 140 °C View Scheme

1: 95 percent / NaOH / ethanol; H2O / 2 h / 20 °C 2: 72 percent / 0.25 h / 140 °C View Scheme

1.1: BuLi / tetrahydrofuran; hexane / 0.5 h / 0 °C 1.2: 81 percent / tetrahydrofuran; hexane / -78 - 20 °C 2.1: 86 percent / Br2; AcOH / 3 h / 80 °C 3.1: 63 percent / dimethylformamide / 14 h / 20 °C 4.1: 95 percent / NaOH / ethanol; H2O / 2 h / 20 °C 5.1: 72 percent / 0.25 h / 140 °C View Scheme

1.1: BuLi / tetrahydrofuran; hexane / 0.5 h / 0 °C 1.2: 81 percent / tetrahydrofuran; hexane / -78 - 20 °C 2.1: 86 percent / Br2; AcOH / 3 h / 80 °C 3.1: 63 percent / dimethylformamide / 14 h / 20 °C 4.1: 95 percent / NaOH / ethanol; H2O / 2 h / 20 °C 5.1: 72 percent / 0.25 h / 140 °C View Scheme