3,4-二氟-2-(2-氯-4-碘苯基氨基)-苯甲酸合成路线 （共 3 条）
反应条件
1: With LiNH2 in tetrahydrofuran T=30 - 50°C; 4 h; Inert atmosphereLarge scale; 2: With hydrogenchloride in tetrahydrofuran; water T=50°C; Inert atmosphereLarge scale; SolventTemperatureReagent/catalyst;
参考文献
Davis, Edward M.; Nanninga, Thomas N.; Tjiong, Howie I.; Winkle, Derick D.
Organic Process Research and Development, 2005 , vol. 9, # 6 p. 843 - 846
反应条件
aqueous hydrochloric acid in acetonitrile
参考文献
Chen, Michael Huai Gu; Davis, Edward Mark; Magano, Javier; Nanninga, Thomas Norman; Winkle, Derick Dale
Patent: US2004/39208 A1, 2004 ;
反应条件
1: With sodium amide Inert atmosphere; 2: With hydrogenchloride in water Inert atmosphere;
参考文献
Davis, Edward M.; Nanninga, Thomas N.; Tjiong, Howie I.; Winkle, Derick D.
Organic Process Research and Development, 2005 , vol. 9, # 6 p. 843 - 846
