1.1: BH3*DMS / tetrahydrofuran / 1.5 h / 10 °C 1.2: 75 percent / 30 percent H2O2 / 2 h / 0 °C 2.1: Dess-Martin periodinane; PhCO2H / CH2Cl2; dimethylsulfoxide / 0.5 h 3.1: 4.4 g / CH2Cl2; dimethylsulfoxide / 10 h / 20 °C 4.1: 78 percent / DIBAL-H / CH2Cl2; hexane / 0 - 20 °C 5.1: 80 percent / TBAF / tetrahydrofuran / 3 h / 20 °C 6.1: 65 percent / (+)-DET; Ti(OPr-i)4; TBHP / 4 h / -20 °C 7.1: 82 percent / pyridine / CH2Cl2 / 10 h / 20 °C View Scheme

1.1: BH3*DMS / tetrahydrofuran / 1.5 h / 10 °C 1.2: 75 percent / 30 percent H2O2 / 2 h / 0 °C 2.1: Dess-Martin periodinane; PhCO2H / CH2Cl2; dimethylsulfoxide / 0.5 h 3.1: 4.4 g / CH2Cl2; dimethylsulfoxide / 10 h / 20 °C 4.1: 78 percent / DIBAL-H / CH2Cl2; hexane / 0 - 20 °C 5.1: 80 percent / TBAF / tetrahydrofuran / 3 h / 20 °C 6.1: 65 percent / (+)-DET; Ti(OPr-i)4; TBHP / 4 h / -20 °C View Scheme

1.1: BH3*DMS / tetrahydrofuran / 1.5 h / 10 °C 1.2: 75 percent / 30 percent H2O2 / 2 h / 0 °C 2.1: Dess-Martin periodinane; PhCO2H / CH2Cl2; dimethylsulfoxide / 0.5 h 3.1: 4.4 g / CH2Cl2; dimethylsulfoxide / 10 h / 20 °C 4.1: 78 percent / DIBAL-H / CH2Cl2; hexane / 0 - 20 °C 5.1: 80 percent / TBAF / tetrahydrofuran / 3 h / 20 °C 6.1: 65 percent / (-)-DET; Ti(OPr-i)4; TBHP / 4 h / -20 °C 7.1: 61 percent / DEAD; TPP / tetrahydrofuran / -20 - 20 °C 8.1: 72 percent / NaOMe / methanol / 3 h / 20 °C 9.1: 75 percent / pyridine / CH2Cl2 / 10 h / 20 °C View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 240 &deg;C<br />2: imidazole / CH₂Cl₂ <br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: K₂CO₃ / acetone<br />2: 240 &deg;C<br />3: imidazole / CH₂Cl₂ <br /> <br /> &nbsp;