N-乙基-2-硝基-4-三氟甲基苯胺合成路线 （共 4 条）
反应条件
triethylamine in N,N-dimethyl-formamide T=100°C; 1 h;
参考文献
WO2011/100838 A1, ;
Page/Page column 24; 25 ;
反应条件
1: With formic acid; triethylamine; palladium 10 on activated carbon in ethanol 2 h; Inert atmosphere; 2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; SIMONEAU, Bruno; DEROY, Patrick; FADER, Lee; FAUCHER, Anne-Marie; GAGNON, Alexandre; GRAND-MAITRE, Chantal; KAWAI, Steven; LANDRY, Serge; MERCIER, Jean-Francois; RANCOURT, Jean
Patent: WO2011/100838 A1, 2011 ;
Location in patent: Page/Page column 24; 25 ;
反应条件
1: triethylamine; formic acid / palladium 10 on activated carbon / ethanol / 2 h / Inert atmosphere
2: tetrahydrofuran / 1.17 h / 20 °C / Inert atmosphere
View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; SIMONEAU, Bruno; DEROY, Patrick; FADER, Lee; FAUCHER, Anne-Marie; GAGNON, Alexandre; GRAND-MAITRE, Chantal; KAWAI, Steven; LANDRY, Serge; MERCIER, Jean-Francois; RANCOURT, Jean
Patent: WO2011/100838 A1, 2011 ;
