N-乙基-4-(三氟甲基)苯-1,2-二胺合成路线 （共 3 条）
反应条件
1: With formic acid; triethylamine; palladium 10 on activated carbon in ethanol 2 h; Inert atmosphere; 2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; SIMONEAU, Bruno; DEROY, Patrick; FADER, Lee; FAUCHER, Anne-Marie; GAGNON, Alexandre; GRAND-MAITRE, Chantal; KAWAI, Steven; LANDRY, Serge; MERCIER, Jean-Francois; RANCOURT, Jean
Patent: WO2011/100838 A1, 2011 ;
Location in patent: Page/Page column 24; 25 ;
反应条件
1: triethylamine / N,N-dimethyl-formamide / 1 h / 100 °C 2: triethylamine; formic acid / palladium 10 on activated carbon / ethanol / 2 h / Inert atmosphere View Scheme
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; SIMONEAU, Bruno; DEROY, Patrick; FADER, Lee; FAUCHER, Anne-Marie; GAGNON, Alexandre; GRAND-MAITRE, Chantal; KAWAI, Steven; LANDRY, Serge; MERCIER, Jean-Francois; RANCOURT, Jean
Patent: WO2011/100838 A1, 2011 ;
反应条件
in tetrahydrofuran
T=20°C; 1.16667 h; Inert atmosphere;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; SIMONEAU, Bruno; DEROY, Patrick; FADER, Lee; FAUCHER, Anne-Marie; GAGNON, Alexandre; GRAND-MAITRE, Chantal; KAWAI, Steven; LANDRY, Serge; MERCIER, Jean-Francois; RANCOURT, Jean
Patent: WO2011/100838 A1, 2011 ;
Location in patent: Page/Page column 24; 25 ;
