5-氧代-1-(2-苯基乙基)吡咯烷-3-羧酸合成路线 (共 4 条)
反应条件
water; potassium hydroxide in tetrahydrofuran
参考文献
Dou, Dengfeng; He, Guijia; Mandadapu, Sivakoteswara Rao; Aravapalli, Sridhar; Kim, Yunjeong; Chang, Kyeong-Ok; Groutas, William C.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 377 - 379
反应条件
1: methanol / 2 h / 20 °C / Reflux 2: water; potassium hydroxide / tetrahydrofuran View Scheme
参考文献
Dou, Dengfeng; He, Guijia; Mandadapu, Sivakoteswara Rao; Aravapalli, Sridhar; Kim, Yunjeong; Chang, Kyeong-Ok; Groutas, William C.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 377 - 379
反应条件
1: methanol / 2 h / 20 °C / Reflux 2: water; potassium hydroxide / tetrahydrofuran View Scheme
参考文献
Dou, Dengfeng; He, Guijia; Mandadapu, Sivakoteswara Rao; Aravapalli, Sridhar; Kim, Yunjeong; Chang, Kyeong-Ok; Groutas, William C.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 377 - 379
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1180513 A1, 2002 ;
Location in patent: Referential example 47 ;
EP 1180513 A1