5-甲基-3-氧代己酸甲酯合成路线 （共 3 条）
反应条件
hydrogen; RuCl2[S-BINAP] in methanol T=20°C; P=76000 Torr; 72 h;
参考文献
Albert, Matthias; Seebach, Dieter; Duchardt, Elke; Schwalbe, Harald
Helvetica Chimica Acta, 2002 , vol. 85, # 2 p. 633 - 658
反应条件
L-(+)-tartaric acid; hydrogen; sodium bromide; nickel in tetrahydrofuran T=60°C; P=750060 Torr; 76 h; Title compound not separated from byproducts;
参考文献
Sugimura, Takashi; Nakagawa, Satoshi; Tai, Akira
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 2 p. 355 - 363
反应条件
1: NH4OAc / methanol / 72 h 2: pyridine / tetrahydrofuran / 24 h / Heating 3: H2, Ru(OCOCF3)2<(R)-binap> / methanol / 18 h / 25 °C / 3040 Torr / other time and catalyst; var. enamido esters 4: 6 N HCl / tetrahydrofuran / 19 h / Heating View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 2, # 7 p. 543 - 554
