4-苯基-2,6-二甲基吡啶合成路线 （共 24 条）
反应条件
1: 1) n-BuLi / 1) THF, -78 deg C, 0.5h, 2) THF, -78 deg C to RT, 1h 2: orthophosphoric acid / 3 h / 130 °C 3: 85 percent / <(C6H5)3P>2NiCl2 / benzene; diethyl ether / 12 h / 80 °C View Scheme
参考文献
Gupta, Arun K.; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar
Tetrahedron, 1990 , vol. 46, # 7 p. 2561 - 2572
反应条件
kaolin; ammonia; acetone T=310°C;
参考文献
Tschitschibabin; Orotschko
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1930 , vol. 62, p. 1201,1203
Chem. Zentralbl., 1930 , vol. 101, # II p. 3768
参考文献
Itoh; Ohsawa; Okada; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 7 p. 3050 - 3052
反应条件
tetrakis(triphenylphosphine) palladium(0); zinc 1.) THF, r.t., 1.5 h, 2.) THF, r.t., 45 h; Yield given. Multistep reaction;
参考文献
Sakamoto, Takao; Kondo, Yoshinori; Murata, Naoko; Yamanaka, Hiroshi
Tetrahedron, 1993 , vol. 49, # 43 p. 9713 - 9720
参考文献
Baeyer; Piccard
Justus Liebigs Annalen der Chemie, 1911 , vol. 384, p. 220
Justus Liebigs Annalen der Chemie, 1915 , vol. 407, p. 339
参考文献
Frank; Seven
Journal of the American Chemical Society, 1949 , vol. 71, p. 2629,2633
参考文献
Tschitschibabin; Orotschko
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1930 , vol. 62, p. 1201,1203
Chem. Zentralbl., 1930 , vol. 101, # II p. 3768
反应条件
sulfuric acid; nitric acid
T=65 - 70°C;
参考文献
Emmert; Diefenbach; Eck
Chemische Berichte, 1927 , vol. 60, p. 2217,2221
反应条件
sulfuric acid; nitric acid
T=65 - 70°C;
参考文献
Emmert; Diefenbach; Eck
Chemische Berichte, 1927 , vol. 60, p. 2217,2221
反应条件
sulfuric acid; nitric acid
T=0°C; 3 h;
参考文献
Prostakov, N. S.; Soldatenkov, A. T.; Krapivko, A. P.; Fomichev, A. A.; Mikaya, A. I.; Ustenko, A. A.
Journal of Organic Chemistry USSR (English Translation), 1982 , p. 958 - 963
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 5 p. 1106 - 1113
