o-羟基-alpha,alpha-二甲基苄醇合成路线 （共 24 条）
反应条件
in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide T=0 - 25°C; 1 h;
参考文献
Cimarelli, Cristina; Palmieri, Gianni
Tetrahedron, 1998 , vol. 54, # 51 p. 15711 - 15720
反应条件
in tetrahydrofuran; diethyl ether T=20°C; 2 h; Cooling with ice;
参考文献
Taisho Pharmaceutical Co., Ltd.; Meiji Seika Kaisha, Ltd.
Patent: EP2287173 A1, 2011 ;
Location in patent: Page/Page column 59 ;
反应条件
in tetrahydrofuran; diethyl ether T=0 - 20°C; 4 h;
参考文献
Johnsson, Richard; Mani, Katrin; Cheng, Fang; Ellervik, Ulf
Journal of Organic Chemistry, 2006 , vol. 71, # 9 p. 3444 - 3451
反应条件
1: With sodium hydride; ethanethiol in N,N-dimethyl-formamide 4 h; RefluxInert atmosphere; 2: With water; ammonium chloride in N,N-dimethyl-formamide Inert atmosphere;
参考文献
Basaric, Nikola; Zabcic, Ivana; Mlinaric-Majerski, Kata; Wan, Peter
Journal of Organic Chemistry, 2010 , vol. 75, # 1 p. 102 - 116
反应条件
acetic acid in tetrahydrofuran; dichloromethane
参考文献
US2014/155596 A1, ;
Page/Page column ;
反应条件
phosphate buffer in tetrahydrofuran; water pH 7.0;
参考文献
Chao, Herbert S.-I.; Berchtold, Glenn A.
Journal of the American Chemical Society, 1981 , vol. 103, # 4 p. 898 - 902
反应条件
water in acetonitrile 1 h; Irradiation;
参考文献
Kalanderopoulos, Peter; Yates, Keith
Journal of the American Chemical Society, 1986 , vol. 108, # 20 p. 6290 - 6295
反应条件
1: 88 percent / tert-butyl hydroperoxide, VO(acac)2 / benzene / 3 h / Heating 2: 83 percent / triethylamine / tetrahydrofuran / 8 h / Ambient temperature 3: 98 percent / Br2 / CCl4 / 0 °C 4: 1.3 g / DBN / diethyl ether / 10 h / 0 °C 5: 92 percent / KF / methanol / 2 h / 0 °C 6: 92 percent / phosphate buffer / tetrahydrofuran; H2O / pH 7.0 View Scheme
参考文献
Chao, Herbert S.-I.; Berchtold, Glenn A.
Journal of the American Chemical Society, 1981 , vol. 103, # 4 p. 898 - 902
反应条件
1: 83 percent / triethylamine / tetrahydrofuran / 8 h / Ambient temperature 2: 98 percent / Br2 / CCl4 / 0 °C 3: 1.3 g / DBN / diethyl ether / 10 h / 0 °C 4: 92 percent / KF / methanol / 2 h / 0 °C 5: 92 percent / phosphate buffer / tetrahydrofuran; H2O / pH 7.0 View Scheme
参考文献
Chao, Herbert S.-I.; Berchtold, Glenn A.
Journal of the American Chemical Society, 1981 , vol. 103, # 4 p. 898 - 902
反应条件
1: 1.3 g / DBN / diethyl ether / 10 h / 0 °C 2: 92 percent / KF / methanol / 2 h / 0 °C 3: 92 percent / phosphate buffer / tetrahydrofuran; H2O / pH 7.0 View Scheme
参考文献
Chao, Herbert S.-I.; Berchtold, Glenn A.
Journal of the American Chemical Society, 1981 , vol. 103, # 4 p. 898 - 902
