4-氯-2-(4-氯苯基)嘧啶-5-羧酸乙酯合成路线 （共 4 条）
反应条件
oxalyl dichloride in dichloromethane T=0°C; 3 h;
参考文献
Palanki, Moorthy S.S.; Erdman, Paul E.; Manning, Anthony M.; Ow, Arnold; Ransone, Lynn J.; Spooner, Cheryl; Suto, Carla; Suto, Mark
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 15 p. 1645 - 1648
反应条件
1: EtONa / ethanol 2: POCl3 View Scheme
参考文献
Palanki, Moorthy S.S.; Erdman, Paul E.; Manning, Anthony M.; Ow, Arnold; Ransone, Lynn J.; Spooner, Cheryl; Suto, Carla; Suto, Mark
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 15 p. 1645 - 1648
反应条件
1: EtONa / ethanol 2: POCl3 View Scheme
参考文献
Palanki, Moorthy S.S.; Erdman, Paul E.; Manning, Anthony M.; Ow, Arnold; Ransone, Lynn J.; Spooner, Cheryl; Suto, Carla; Suto, Mark
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 15 p. 1645 - 1648
反应条件
1: With zinc in tetrahydrofuran; acetic acid T=60°C; 18 h; 2: With zinc in acetic acid 24 h;
参考文献
SmithKline Beecham p.l.c.
Patent: US2004/167142 A1, 2004 ;
Location in patent: Page/Page column 10 ;
