6-溴-2,4,4-三甲基-2,4-二氢-1H-苯并[d][1,3]噁嗪合成路线 (共 3 条)
参考文献
Wyeth; Ligand Pharmaceuticals, Inc.
Patent: US6498154 B1, 2002 ;
反应条件
in toluene T=20°C; 0.166667 h;
参考文献
American Home Products Corporation; Ligand Pharmaceuticals, Inc.
Patent: US6358948 B1, 2002 ;
Location in patent: Example 13 ;
反应条件
1: diethyl ether / 0 °C 2: p-TsOH / toluene / 20 °C View Scheme
参考文献
Zhang, Puwen; Terefenko, Eugene A.; Fensome, Andrew; Zhang, Zhiming; Zhu, Yuan; Cohen, Jeffrey; Winneker, Richard; Wrobel, Jay; Yardley, John
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 5 p. 787 - 790