咪唑并[1,2-a]吡啶-3-基甲醇合成路线 （共 10 条）
反应条件
sodium tetrahydroborate in methanol T=5°C; 6 h; Reflux;
参考文献
Chioua, Mourad; Soriano, Elena; Infantes, Lourdes; Jimeno, M. Luisa; Marco-Contelles, Jose; Samadi, Abdelouahid
European Journal of Organic Chemistry, 2013 , # 1 p. 35 - 39
反应条件
silver trifluoromethanesulfonate in acetonitrile 2 h; Inert atmosphereReflux; TimeReagent/catalyst;
参考文献
Chandra Mohan, Darapaneni; Nageswara Rao, Sadu; Adimurthy, Subbarayappa
Journal of Organic Chemistry, 2013 , vol. 78, # 3 p. 1266 - 1272
反应条件
1: 30 percent / POCl3 2: NaBH4 / methanol View Scheme
参考文献
Blaewska, Katarzyna M.; Ni, Feng; Haiges, Ralf; Kashemirov, Boris A.; Coxon, Fraser P.; Stewart, Charlotte A.; Baron, Rudi; Rogers, Michael J.; Seabra, Miguel C.; Ebetino, Frank H.; McKenna, Charles E.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 10 p. 4820 - 4826
反应条件
sodium acetate in water; acetic acid 96 h; Heating;
参考文献
Teulade, Jean C.; Bonnet, Pierre A.; Rieu, Jean N.; Viols, Henry; Chapat, Jean P.; et al.
Journal of Chemical Research, Miniprint, 1986 , # 6 p. 1842 - 1874
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 1 h / 20 °C / |Inert atmosphere 2: silver trifluoromethanesulfonate / acetonitrile / 24 h / 85 °C / |Inert atmosphere 3: selenium(IV) oxide; acetic acid / 16 h / |Reflux 4: sodium tetrahydroborate / methanol / 6 h / 5 °C / |Reflux View Scheme
参考文献
Chioua, Mourad; Soriano, Elena; Infantes, Lourdes; Jimeno, M. Luisa; Marco-Contelles, Jose; Samadi, Abdelouahid
European Journal of Organic Chemistry, 2013 , # 1 p. 35 - 39
反应条件
1: silver trifluoromethanesulfonate / acetonitrile / 24 h / 85 °C / |Inert atmosphere 2: selenium(IV) oxide; acetic acid / 16 h / |Reflux 3: sodium tetrahydroborate / methanol / 6 h / 5 °C / |Reflux View Scheme
参考文献
Chioua, Mourad; Soriano, Elena; Infantes, Lourdes; Jimeno, M. Luisa; Marco-Contelles, Jose; Samadi, Abdelouahid
European Journal of Organic Chemistry, 2013 , # 1 p. 35 - 39
反应条件
1: tert-butyl alcohol 2: sodium hydride / N,N-dimethyl-formamide / 1 h / 20 °C / |Inert atmosphere 3: silver trifluoromethanesulfonate / acetonitrile / 24 h / 85 °C / |Inert atmosphere 4: selenium(IV) oxide; acetic acid / 16 h / |Reflux 5: sodium tetrahydroborate / methanol / 6 h / 5 °C / |Reflux View Scheme
参考文献
Gueiffier, Alain; Lhassani, Mohammed; Elhakmaoui, Ahmed; Snoeck, Robert; Andrei, Graciela; Chavignon, Olivier; Teulade, Jean-Claude; Kerbal, Abdelali; Essassi, El Mokhtar; Debouzy, Jean-Claude; Witvrouw, Myriam; Blache, Yves; Balzarini, Jan; De Clercq, Erik; Chapat, Jean-Pierre
Journal of Medicinal Chemistry, 1996 , vol. 39, # 14 p. 2856 - 2859
反应条件
1: silver trifluoromethanesulfonate / acetonitrile / 2 h / |Inert atmosphere; |Reflux 2: selenium(IV) oxide; acetic acid / 16 h / |Reflux 3: sodium tetrahydroborate / methanol / 6 h / 5 °C / |Reflux View Scheme
参考文献
Chioua, Mourad; Soriano, Elena; Infantes, Lourdes; Jimeno, M. Luisa; Marco-Contelles, Jose; Samadi, Abdelouahid
European Journal of Organic Chemistry, 2013 , # 1 p. 35 - 39
反应条件
1: selenium(IV) oxide; acetic acid / 16 h / |Reflux 2: sodium tetrahydroborate / methanol / 6 h / 5 °C / |Reflux View Scheme
参考文献
Chioua, Mourad; Soriano, Elena; Infantes, Lourdes; Jimeno, M. Luisa; Marco-Contelles, Jose; Samadi, Abdelouahid
European Journal of Organic Chemistry, 2013 , # 1 p. 35 - 39
反应条件
thionyl chloride Heating;
参考文献
Blaewska, Katarzyna M.; Ni, Feng; Haiges, Ralf; Kashemirov, Boris A.; Coxon, Fraser P.; Stewart, Charlotte A.; Baron, Rudi; Rogers, Michael J.; Seabra, Miguel C.; Ebetino, Frank H.; McKenna, Charles E.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 10 p. 4820 - 4826
