(-)-1,2,3a,12c-四氢-6,8-二羟基-7H-呋喃并(3',2':4,5)呋喃并(2,3-c)氧杂蒽-7-酮合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate P=1551.44 Torr; 12 h;
参考文献
Henry, Kevin M.; Townsend, Craig A.
Journal of the American Chemical Society, 2005 , vol. 127, # 11 p. 3724 - 3733
反应条件
1.1: n-BuLi / pentane / 0.02 h / -40 °C 1.2: 92 percent / tetrahydrofuran; pentane / 0.5 h / -40 - 0 °C 2.1: 50 percent / Dess-Martin periodinane / CH2Cl2 / 0 - 20 °C 3.1: TBAF / tetrahydrofuran / 1 h / Heating 3.2: 86 percent / aq. HCl / tetrahydrofuran / 0.5 h / 0 - 25 °C 4.1: H2 / Pd/C / ethyl acetate / 12 h / 1551.44 Torr View Scheme
参考文献
Henry, Kevin M.; Townsend, Craig A.
Journal of the American Chemical Society, 2005 , vol. 127, # 11 p. 3724 - 3733
反应条件
1.1: 50 percent / Dess-Martin periodinane / CH2Cl2 / 0 - 20 °C 2.1: TBAF / tetrahydrofuran / 1 h / Heating 2.2: 86 percent / aq. HCl / tetrahydrofuran / 0.5 h / 0 - 25 °C 3.1: H2 / Pd/C / ethyl acetate / 12 h / 1551.44 Torr View Scheme
参考文献
Henry, Kevin M.; Townsend, Craig A.
Journal of the American Chemical Society, 2005 , vol. 127, # 11 p. 3724 - 3733
反应条件
1.1: TBAF / tetrahydrofuran / 1 h / Heating 1.2: 86 percent / aq. HCl / tetrahydrofuran / 0.5 h / 0 - 25 °C 2.1: H2 / Pd/C / ethyl acetate / 12 h / 1551.44 Torr View Scheme
参考文献
Henry, Kevin M.; Townsend, Craig A.
Journal of the American Chemical Society, 2005 , vol. 127, # 11 p. 3724 - 3733
反应条件
1.1: TBAF / tetrahydrofuran / 1 h / Heating 1.2: 86 percent / aq. HCl / tetrahydrofuran / 0.5 h / 0 - 25 °C 2.1: H2 / Pd/C / ethyl acetate / 12 h / 1551.44 Torr View Scheme
参考文献
Henry, Kevin M.; Townsend, Craig A.
Journal of the American Chemical Society, 2005 , vol. 127, # 11 p. 3724 - 3733
反应条件
1.1: n-BuLi / pentane / 0.02 h / -40 °C 1.2: 92 percent / tetrahydrofuran; pentane / 0.5 h / -40 - 0 °C 2.1: 50 percent / Dess-Martin periodinane / CH2Cl2 / 0 - 20 °C 3.1: TBAF / tetrahydrofuran / 1 h / Heating 3.2: 86 percent / aq. HCl / tetrahydrofuran / 0.5 h / 0 - 25 °C 4.1: H2 / Pd/C / ethyl acetate / 12 h / 1551.44 Torr View Scheme
参考文献
Henry, Kevin M.; Townsend, Craig A.
Journal of the American Chemical Society, 2005 , vol. 127, # 11 p. 3724 - 3733
