2-氯-6-甲基烟酸合成路线

30529-70-52-氯-6-甲基烟酸

689259-06-1(2-氯-6-甲基吡啶-3-基)甲醇

参考文献

ASTRAZENECA AB
Patent: WO2009/5460 A1, 2009 ;
Location in patent: Page/Page column 35-36 ;
WO 2009/005460 A1

30529-70-52-氯-6-甲基烟酸

846021-26-92-氨基-6-甲基-3-吡啶羧酸

参考文献

ARRAY BIOPHARMA INC.
Patent: WO2005/51304 A2, 2005 ;
Location in patent: Page/Page column 145-146 ;
WO 2005/051304 A2

30529-70-52-氯-6-甲基烟酸

49667-29-0

参考文献

Gong, Leyi; Tan, Yun-Chou; Boice, Genevieve; Abbot, Sarah; McCaleb, Kristen; Iyer, Pravin; Zuo, Fengrong; Porto, Joseph Dal; Wong, Brian; Jin, Sue; Chang, Alice; Tran, Patricia; Hsieh, Gary; Niu, Linghao; Shao, Ada; Reuter, Deborah; Lukacs, Christine M.; Ursula Kammlott; Kuglstatter, Andreas; Goldstein, David
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7381 - 7387

30529-70-52-氯-6-甲基烟酸

59663-04-6

参考文献

Atkinson, Paul; Findlay, Karen S.; Kielar, Filip; Pal, Robert; Parker, David; Poole, Robert A.; Puschmann, Horst; Richardson, Siobhan L.; Stenson, Philip A.; Thompson, Amber L.; Yu, Junhau
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 9 p. 1707 - 1722

30529-70-52-氯-6-甲基烟酸

59663-08-0

参考文献

Atkinson, Paul; Findlay, Karen S.; Kielar, Filip; Pal, Robert; Parker, David; Poole, Robert A.; Puschmann, Horst; Richardson, Siobhan L.; Stenson, Philip A.; Thompson, Amber L.; Yu, Junhau
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 9 p. 1707 - 1722

30529-70-52-氯-6-甲基烟酸

613660-40-5

参考文献

Haviv, Fortuna; Bradley, Michael F.; Henkin, Jack; Dinges, Jurgen; Sauer, Daryl R.; Kolaczkowski, Lawrence; Vasudevan, Anil; Park, David C.
Patent: US2004/14744 A1, 2004 ;

30529-70-52-氯-6-甲基烟酸+

109-05-7哌可啉

613660-42-7

参考文献

Haviv, Fortuna; Bradley, Michael F.; Henkin, Jack; Dinges, Jurgen; Sauer, Daryl R.; Kolaczkowski, Lawrence; Vasudevan, Anil; Park, David C.
Patent: US2004/14744 A1, 2004 ;

626-58-44-甲基哌啶+

30529-70-52-氯-6-甲基烟酸

613660-44-9

参考文献

Haviv, Fortuna; Bradley, Michael F.; Henkin, Jack; Dinges, Jurgen; Sauer, Daryl R.; Kolaczkowski, Lawrence; Vasudevan, Anil; Park, David C.
Patent: US2004/14744 A1, 2004 ;

30529-70-52-氯-6-甲基烟酸+

1484-80-62-乙基哌啶

613660-46-1

参考文献

Haviv, Fortuna; Bradley, Michael F.; Henkin, Jack; Dinges, Jurgen; Sauer, Daryl R.; Kolaczkowski, Lawrence; Vasudevan, Anil; Park, David C.
Patent: US2004/14744 A1, 2004 ;

30529-70-52-氯-6-甲基烟酸+

108-95-2苯酚

54530-64-2

参考文献

Atkinson, Paul; Findlay, Karen S.; Kielar, Filip; Pal, Robert; Parker, David; Poole, Robert A.; Puschmann, Horst; Richardson, Siobhan L.; Stenson, Philip A.; Thompson, Amber L.; Yu, Junhau
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 9 p. 1707 - 1722