4-氯-6-硝基-1,8-萘啶-3-甲腈合成路线 (共 3 条)
反应条件
trichlorophosphate 24 h; Heating;
参考文献
Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
反应条件
1: 90 percent / SOCl2 / 5 h / Heating 2: 70 percent / iPr2NEt / CH2Cl2 / 16 h / Heating 3: 100 percent / aq. NH3 / ethanol / 4 h / Heating 4: 70 percent / POCl3 / 24 h / Heating View Scheme
参考文献
Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416
反应条件
1: 70 percent / iPr2NEt / CH2Cl2 / 16 h / Heating 2: 100 percent / aq. NH3 / ethanol / 4 h / Heating 3: 70 percent / POCl3 / 24 h / Heating View Scheme
参考文献
Wissner, Allan; Hamann, Philip R.; Nilakantan, Ramaswamy; Greenberger, Lee M.; Ye, Fei; Rapuano, Timothy A.; Loganzo, Frank
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1411 - 1416