caesium carbonate; triphenylphosphine; palladium diacetate in DMF (N,N-dimethyl-formamide) T=20 - 140°C; 40 h;

1: 1-methyl-1H-imidazole; immobilized p-iodobenzoate With palladium diacetate; caesium carbonate; triphenylphosphine in N,N-dimethyl-formamide T=120°C; Solid phase reaction; 16 h; 2: sodium methylate in tetrahydrofuran; methanol T=20°C; Substitution; 6 h; Further stages.;