1: With tri-isopropoxy-borane; lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 0.5 h; Nitrogen atmosphere; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
American Home Products Corporation; Ligand Pharmaceuticals, Inc.
Patent: US6355648 B1, 2002 ;
Location in patent: Page column 64 ;
US 6355648 B1
