反应条件
<b>Multi-step reaction with 5 steps<br /> </b>1: 92 percent / MeSO<sub>3</sub>H / 0 - 20 °C<br />2: 95 percent / Et<sub>3</sub>N / CCl<sub>4</sub> / 0 - 20 °C<br />3: 93 percent / liquid NH<sub>3</sub>; Li / tetrahydrofuran / -78 °C<br />4: 100 percent / BBr<sub>3</sub> / CH<sub>2</sub>Cl<sub>2</sub> / 0 - 20 °C<br />5: 77 percent / p-TsOH*H<sub>2</sub>O<br /> <br />
参考文献
Huffman, John W.; Miller, John R. A.; Liddle, John; Yu, Shu; Thomas, Brian F.; Wiley, Jenny L.; Martin, Billy R. Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 7 p. 1397 - 1410
