2-甲基-2-丙基4-(3-氯苄基)-1-哌嗪羧酸酯合成路线 (共 3 条)
反应条件
Na[HB(OMe)3]; acetic acid in dichloromethane T=20°C; 72 h;
参考文献
Castelhano, Arlindo; McKibben, Bryan; Steinig, Arno
Patent: US2003/229067 A1, 2003 ;
Location in patent: Page 31 ;
US 20030229067 A1
反应条件
potassium carbonate in ethanol Heating;
参考文献
Bourrain, Sylvie; Collins, Ian; Neduvelil, Joseph G.; Rowley, Michael; Leeson, Paul D.; Patel, Smita; Patel, Shil; Emms, Frances; Marwood, Rosemarie; Chapman, Kerry L.; Fletcher, Alan E.; Showell, Graham A.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 10 p. 1731 - 1743
反应条件
trifluoroacetic acid in dichloromethane Ambient temperature;
参考文献
Sadeghzadeh, Masoud; Sheibani, Shahab; Ghandi, Mehdi; Daha, Fariba Johari; Amanlou, Massoud; Arjmand, Mohammad; Hasani Bozcheloie, Abolfazl
European Journal of Medicinal Chemistry, 2013 , vol. 64, p. 488 - 497