2-(2,6-二甲基苯基)乙醇合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Reduction; 4 h; Heating;
参考文献
Finkielsztein, Liliana M.; Alesso, Elba N.; Lantano, Beatriz; Aguirre, Jose M.; Iglesias, Graciela Y. Moltrasio
Journal of Chemical Research, Miniprint, 1999 , # 6 p. 1561 - 1566
反应条件
(i) Mg, Et2O, (ii) /BRN= 102378/; Multistep reaction;
参考文献
Ng; McMorris
Canadian Journal of Chemistry, 1984 , vol. 62, # 10 p. 1945 - 1953
反应条件
1: 81 percent / ZnCl2 / CH2Cl2 / 1 h / Heating 2: 83 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Finkielsztein, Liliana M.; Alesso, Elba N.; Lantano, Beatriz; Aguirre, Jose M.; Iglesias, Graciela Y. Moltrasio
Journal of Chemical Research, Miniprint, 1999 , # 6 p. 1561 - 1566
反应条件
1: 93 percent / concd. HCl / 2 h / Heating 2: 81 percent / ZnCl2 / CH2Cl2 / 1 h / Heating 3: 83 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Finkielsztein, Liliana M.; Alesso, Elba N.; Lantano, Beatriz; Aguirre, Jose M.; Iglesias, Graciela Y. Moltrasio
Journal of Chemical Research, Miniprint, 1999 , # 6 p. 1561 - 1566
反应条件
1: NaNO2, 48 percent HBr / H2O / 10 °C 2: copper bronze / Heating 3: 1.) Mg turnings / 1.) THF, reflux, 30 min; 2.) THF, reflux, 3 h View Scheme
参考文献
Ng; McMorris
Canadian Journal of Chemistry, 1984 , vol. 62, # 10 p. 1945 - 1953
反应条件
1: SOCl2 / benzene 2: N2H4*H2O / propan-1-ol / Heating View Scheme
参考文献
Bream,J.B. et al.
Journal of Medicinal Chemistry, 1970 , vol. 13, # 6 p. 1051 - 1057
反应条件
pyridine; thionyl chloride in chloroform Chlorination; 0.75 h; Heating;
参考文献
Finkielsztein, Liliana M.; Alesso, Elba N.; Lantano, Beatriz; Aguirre, Jose M.; Iglesias, Graciela Y. Moltrasio
Journal of Chemical Research, Miniprint, 1999 , # 6 p. 1561 - 1566
反应条件
1: 79 percent / pyridine / 4 h / Heating
2: AlCl3 / CS2 / 4 h / Ambient temperature
3: 15 percent / conc. H2SO4 / 4 h / 90 °C
View Scheme
参考文献
Sheridan; Lemon; Frankish; McArdle; Higgins; James; Bhandari
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 7 p. 603 - 608
反应条件
1: SOCl2 / benzene
2: N2H4*H2O / propan-1-ol / Heating
3: H2O
View Scheme
参考文献
Bream,J.B. et al.
Journal of Medicinal Chemistry, 1970 , vol. 13, # 6 p. 1051 - 1057
