1-(2-氯苄基)-1H-吲哚-2,3-二酮合成路线 （共 2 条）
反应条件
1: indole-2,3-dione With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 2 h; 2: 2-chlorophenylmethyl bromide in tetrahydrofuran; mineral oil T=20°C;
参考文献
WAYNE STATE UNIVERSITY; DEPARTMENT OF VETERANS AFFAIRS; REGENTS OF THE UNIVERSITY OF MICHIGAN; RISHI, Arun, K.; LARSEN, Scott, D.
Patent: WO2013/33392 A1, 2013 ;
Location in patent: Page/Page column 62-63 ;
反应条件
1: N-bromosuccinimide; benzoyl peroxide / CCl4 / 10 h / Heating 2: 1.29 g / potassium carbonate; potassium iodide / acetonitrile / 4 h / 20 °C View Scheme
参考文献
Makhija, Mahindra T.; Kasliwal, Rajesh T.; Kulkarni, Vithal M.; Neamati, Nouri
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 9 p. 2317 - 2333
