2-乙酰氨基-3,4,6-三-O-乙酰-2-脱氧-α-D-吡喃葡萄糖酰基氯合成路线 （共 104 条）
反应条件
silver carbonate in dichloromethane
参考文献
RajanBabu; Ayers, Timothy A.; Halliday, Gary A.; You, Kimberly K.; Calabrese, Joseph C.
Journal of Organic Chemistry, 1997 , vol. 62, # 17 p. 6012 - 6025
反应条件
tin(II) trifluoromethanesulfonate; 4 A molecular sieve; N,N,N',N'-tetramethyl-urea in dichloromethane 48 h; Ambient temperature;
参考文献
Lubineau, Andre; Gallic, Joelle Le; Malleron, Annie
Tetrahedron Letters, 1987 , vol. 28, # 42 p. 5041 - 5044
反应条件
1: CHCl3; HCl; water 2: water; chloroform; acetic acid anhydride 3: acetic acid; hydrogen bromide 4: chloroform; silver oxide; sodium sulfate / Reagens 4: Jod View Scheme
参考文献
Inouye et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 4218,4220
参考文献
Vega-Perez, Jose M.; Palo-Nieto, Carlos; Perinan, Ignacio; Vega-Holm, Margarita; Calderon-Montano, Jose M.; Lopez-Lazaro, Miguel; Iglesias-Guerra, Fernando
European Journal of Organic Chemistry, 2012 , # 6 p. 1237 - 1252
反应条件
1.1: acetonitrile / 0.17 h / 20 °C / Molecular sieve 1.2: 25 h / 55 - 80 °C 2.1: sodium methylate / methanol / 2 h / 20 °C 2.2: Amberlite IR-120 (H+ form) 3.1: Jack bean N-acetyl-β-D-glucosaminidase / isopropyl alcohol / 48 h / 37 °C / pH 5 / aq. sodium phosphate buffer; Enzymatic reaction View Scheme
参考文献
Garcia-Alvarez, Isabel; Groult, Hugo; Casas, Josefina; Barreda-Manso, M. Asuncion; Yanguas-Casas, Natalia; Nieto-Sampedro, Manuel; Romero-Ramirez, Lorenzo; Fernandez-Mayoralas, Alfonso
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6949 - 6955
反应条件
15-crown-5; sodium hydrogencarbonate in acetonitrile T=20°C;
参考文献
Kur'yanov; Chupakhina; Zemlyakov; Kotlyar; Kamalov; Chirva
Russian Journal of Bioorganic Chemistry, 2001 , vol. 27, # 6 p. 385 - 389
反应条件
1: 26 percent / Hg(CN)2, HgBr2 2: 6.88 g / NaOMe / methanol / Ambient temperature 3: p-toluenesulphonic acid / acetonitrile / 60 h / 60 °C 4: NaH / tetrahydrofuran 5: NaCNBH3, molecular sieves 3 Angstroem, etheral HCl / tetrahydrofuran / 0.75 h View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 70, # 10 p. 2607 - 2617
反应条件
1.1: acetonitrile / 0.17 h / 20 °C / Molecular sieve 1.2: 25 h / 55 - 80 °C 2.1: sodium methylate / methanol / 2 h / 20 °C 2.2: Amberlite IR-120 (H+ form) 3.1: Jack bean N-acetyl-β-D-glucosaminidase / isopropyl alcohol / 48 h / 37 °C / pH 5 / aq. sodium phosphate buffer; Enzymatic reaction View Scheme
参考文献
Garcia-Alvarez, Isabel; Groult, Hugo; Casas, Josefina; Barreda-Manso, M. Asuncion; Yanguas-Casas, Natalia; Nieto-Sampedro, Manuel; Romero-Ramirez, Lorenzo; Fernandez-Mayoralas, Alfonso
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6949 - 6955
反应条件
1: tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide / dichloromethane / 2.5 h / 20 °C 2: methanol; sodium methylate / 20 °C 3: sodium hydroxide; Thermus nonproteolyticus HG102 E338A mutant; glycine / N,N-dimethyl-formamide / 48 h / 45 °C / pH 8.8 / |Enzymatic reaction View Scheme
参考文献
Wei, Jinhua; Lv, Xun; Lue, Yang; Yang, Gangzhu; Fu, Lifeng; Yang, Liu; Wang, Jianjun; Gao, Jianhui; Cheng, Shuihong; Duan, Qian; Jin, Cheng; Li, Xuebing
European Journal of Organic Chemistry, 2013 , # 12 p. 2414 - 2419
反应条件
1: 65 percent / tetrabutylammonium bromide; aq. NaOH / CH2Cl2 / 0.83 h / 20 °C 2: 99 percent / NaOMe / methanol / 1 h / 20 °C View Scheme
参考文献
Chung, Sang J.; Takayama, Shuichi; Wong, Chi-Huey
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 23 p. 3359 - 3364
