2-乙酰氨基-3,4,6-三-O-乙酰-2-脱氧-α-D-吡喃葡萄糖酰基氯合成路线 （共 104 条）
反应条件
sodium methylate in dichloromethane 0.5 h; Ambient temperature;
参考文献
Wang, Lai-Xi; Lee, Yuan C.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 6 p. 581 - 591
反应条件
1: 78 percent / Ag2CO3 / CH2Cl2 2: 95 percent / Biorad AGMP(OH-) resin / methanol View Scheme
参考文献
RajanBabu; Ayers, Timothy A.; Halliday, Gary A.; You, Kimberly K.; Calabrese, Joseph C.
Journal of Organic Chemistry, 1997 , vol. 62, # 17 p. 6012 - 6025
反应条件
1: sodium azide; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate / dichloromethane / 3 h / 20 °C 2: platinum(IV) oxide; hydrogen / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere 3: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 4 h / 20 °C / Inert atmosphere 4: trifluoroacetic acid / water / 3 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 17 p. 4973 - 4975
反应条件
1: 84 percent / tetrabutylammonium hydrogen sulfate, 1M NaOH / CH2Cl2 / 0.75 h / Ambient temperature 2: NaOMe / methanol / Ambient temperature View Scheme
参考文献
Roy, Rene; Tropper, Francois D.
Canadian Journal of Chemistry, 1991 , vol. 69, # 5 p. 817 - 821
反应条件
tin(II) trifluoromethanesulfonate; 3 A molecular sieve; N,N,N',N'-tetramethyl-urea in dichloromethane 16 h; Ambient temperature1.) CH2Cl2, 2.) 16 h, r.t.;
参考文献
Carbohydrate Research, , vol. 212, p. 267 - 271
反应条件
15-crown-5; sodium iodide in 1,2-dichloro-ethane T=70°C; Title compound not separated from byproducts;
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 24, # 4 p. 282 - 283
反应条件
1: aq. NaOH solution; acetone 2: sodium methylate; methanol View Scheme
参考文献
Heyworth et al.
Journal of the Chemical Society, 1959 , p. 4121
反应条件
sodium azide; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate in dichloromethane
参考文献
Shin, Injae; Jung, Hyuk-Jun; Lee, Myung-Ryul
Tetrahedron Letters, 2001 , vol. 42, # 7 p. 1325 - 1328
反应条件
1.1: acetonitrile / 0.17 h / 20 °C / Molecular sieve 1.2: 25 h / 55 - 80 °C 2.1: sodium methylate / methanol / 2 h / 20 °C 2.2: Amberlite IR-120 (H+ form) 3.1: Jack bean N-acetyl-β-D-glucosaminidase / isopropyl alcohol / 48 h / 37 °C / pH 5 / aq. sodium phosphate buffer; Enzymatic reaction View Scheme
参考文献
Garcia-Alvarez, Isabel; Groult, Hugo; Casas, Josefina; Barreda-Manso, M. Asuncion; Yanguas-Casas, Natalia; Nieto-Sampedro, Manuel; Romero-Ramirez, Lorenzo; Fernandez-Mayoralas, Alfonso
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6949 - 6955
反应条件
1: 46.2 percent / Et3N / acetonitrile / 4 h / 40 °C 2: 91.3 percent / H2 / 10percent Pd/C / ethanol; dioxane / 3 h / 760 Torr / Ambient temperature 3: 61.8 percent / 28percent NaOMe / methanol; acetonitrile; CHCl3 / 1 h / Ambient temperature View Scheme
参考文献
Roy, Rene; Tropper, Francois D.; Morrison, Tara; Boratynski, Janusz
Journal of the Chemical Society, Chemical Communications, 1991 , # 7 p. 536 - 538
