4-氨基-5-氧代-8h-吡啶并[2,3-d]嘧啶合成路线 （共 3 条）
反应条件
in 2-ethoxy-ethanol 20 h; Heating / reflux;
参考文献
MERCK PATENT GMBH
Patent: WO2005/47283 A1, 2005 ;
Location in patent: Page/Page column 64 ;
WO 2005/047283 A1
反应条件
in 2-ethoxy-ethanol 20 h; Heating / reflux;
参考文献
MERCK PATENT GMBH
Patent: WO2005/105797 A1, 2005 ;
Location in patent: Page/Page column 62 ;
WO 2005/105797 A1
反应条件
1: 80 percent / acetonitrile / 20 h / Heating 2: 89 percent / 2-ethoxy-ethanol / 30 h / Heating View Scheme
参考文献
Girardet; Gunic; Esler; Cieslak; Pietrzkowski; Wang
Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3704 - 3713
