2-三氟甲基嘧啶-5-羧酸合成路线 （共 4 条）
反应条件
sodium hydroxide in tetrahydrofuran Hydrolysis;
参考文献
Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto
Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004
反应条件
sodium hydroxide in methanol T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 22 p. 4898 - 4906
反应条件
1: 55 percent / NaOEt / ethanol / 6 h / Heating 2: 85 percent / aq. NaOH / tetrahydrofuran View Scheme
参考文献
Journal of medicinal chemistry, , vol. 43, # 21 p. 3995 - 4004
反应条件
1: methanol / Heating 2: aq. NaOH / methanol / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 22 p. 4898 - 4906
