2-甲基-5-硝基-1H-咪唑-1-乙基甲磺酸酯合成路线 （共 5 条）
反应条件
triethylamine in dichloromethane T=20°C; 4 h;
参考文献
Hay; Wilson; Moselen; Palmer; Denny
Journal of Medicinal Chemistry, 1994 , vol. 37, # 3 p. 381 - 391
反应条件
sodium bromide in N,N-dimethyl-formamide T=100°C; 4 h;
参考文献
Hay, Michael P.; Lee, Ho H.; Wilson, William R.; Roberts, Peter B.; Denny, William A.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1928 - 1941
反应条件
1: 62 percent / NaBr / dimethylformamide / 4 h / 100 °C 2: 45 percent / NaI / acetone / 4 h / Heating View Scheme
参考文献
Hay, Michael P.; Lee, Ho H.; Wilson, William R.; Roberts, Peter B.; Denny, William A.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1928 - 1941
反应条件
sodium hydrogensulfide in N,N-dimethyl-formamide
T=20°C; 48 h;
参考文献
De Martino, Gabriella; Regina, Giuseppe La; Pasquali, Alessandra Di; Ragno, Rino; Bergamini, Alberto; Ciaprini, Chiara; Sinistro, Anna; Maga, Giovanni; Crespan, Emmanuele; Artico, Marino; Silvestri, Romano
Journal of Medicinal Chemistry, 2005 , vol. 48, # 13 p. 4378 - 4388
反应条件
sodium azide in N,N-dimethyl-formamide
T=100°C; 4 h;
参考文献
Hay, Michael P.; Lee, Ho H.; Wilson, William R.; Roberts, Peter B.; Denny, William A.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 11 p. 1928 - 1941
