2-[(3-硝基苯基)甲氧基]异吲哚-1,3-二酮合成路线 (共 3 条)
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; 19 h;
参考文献
CRYPTOPHARMA PTY LTD; MCALLISTER, David, James; LAMBERT, John, Nicholas
Patent: WO2004/101595 A1, 2004 ;
Location in patent: Page 78-79 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=0 - 50°C; Mitsunobu reaction;
参考文献
Alanine, Alexander; Bourson, Anne; Buettelmann, Bernd; Gill, Ramanjit; Heitz, Marie-Paule; Mutel, Vincent; Pinard, Emmanuel; Trube, Gerhard; Wyler, Rene
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 19 p. 3155 - 3159
反应条件
1: With hydrazine in ethanol; dichloromethane; water 18 h; Heating / reflux; 2: With hydrogenchloride in diethyl ether; ethanol
参考文献
CRYPTOPHARMA PTY LTD; MCALLISTER, David, James; LAMBERT, John, Nicholas
Patent: WO2004/101595 A1, 2004 ;
Location in patent: Page 79 ;