1-乙酰基-4-亚甲基哌啶合成路线 (共 1 条)
反应条件
1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=0 - 20°C; Wittig Olefination; 0.5 h; Inert atmosphere; 2: 1-acetyl-4-oxopiperidine in tetrahydrofuran; hexane T=20°C; Wittig Olefination; 24 h; Inert atmosphere;
参考文献
Zhang, Chengwei; Li, Zhaodong; Zhu, Lin; Yu, Limei; Wang, Zhentao; Li, Chaozhong
Journal of the American Chemical Society, 2013 , vol. 135, # 38 p. 14082 - 14085