反应条件
1.1: NBS; AIBN / chlorobenzene / 1.5 h / 90 °C 2.1: 33.0 g / i-Pr2NEt / dimethylformamide / 2 h / 20 °C 3.1: 87 percent / HCl; HCO2H / 10 percent Pd/C/water / diethyl ether / 3.5 h / 20 °C / atmospheric pressure 4.1: Et3N / CH2Cl2 / 24 h / 20 °C 4.2: 71 percent / Et3N / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Sasaki, Satoshi; Cho, Nobuo; Nara, Yoshi; Harada, Masataka; Endo, Satoshi; Suzuki, Nobuhiro; Furuya, Shuichi; Fujino, Masahiko
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 113 - 124
