4-(4-溴苯基)-4-氧丁酸乙酯合成路线 （共 9 条）
反应条件
sulfuric acid 3 h; Heating;
参考文献
Ding, Pingyu; Helquist, Paul; Miller, Marvin J.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 4 p. 1648 - 1657
反应条件
formic acid; [Pd(PPh3)2(OAc)2]; tributyl-amine in N,N-dimethyl-formamide T=60°C;
参考文献
Arcadi, A.; Cacchi, S.; Marinelli, F.; Misiti, D.
Tetrahedron Letters, 1988 , vol. 29, # 12 p. 1457 - 1460
反应条件
formic acid; [Pd(PPh3)2(OAc)2]; tributyl-amine in N,N-dimethyl-formamide T=60°C; 5 h;
参考文献
Arcadi, A.; Cacchi, S.; Marinelli, F.; Misiti, D.
Tetrahedron Letters, 1988 , vol. 29, # 12 p. 1457 - 1460
反应条件
Cu(1,1,1,5,5,5-hexafluoroacetylacetonate)2 in o-di-fluorobenzene Heating;
参考文献
Huang, Dan; Yan, Ming; Zhao, Wei-Jie; Shen, Qi
Synthetic Communications, 2005 , vol. 35, # 5 p. 745 - 750
反应条件
1: 94 percent / AlCl3 / -5 - 20 °C 2: 84 percent / N,N'-dicyclohexylcarbodiimide; 4-(N,N-dimethylamido)pyridine / CH2Cl2 / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 22 p. 7283 - 7286
反应条件
tris(4-methoxyphenyl)-phosphine in chloroform T=60°C; 24 h; Overall yield = 62 percent;
参考文献
Synthetic Communications, , vol. 43, # 6 p. 848 - 858
反应条件
n-butyllithium 1.) ether, 0 deg C, 15 min, 2.) ether, a) -78 deg C, 1 h, b) RT, 1 h; Yield given. Multistep reaction;
参考文献
Heterocycles, , vol. 14, # 3 p. 291 - 293
反应条件
tetrakis(triphenylphosphine) palladium(0); zinc copper
参考文献
Chemistry Letters, , # 9 p. 881 - 882
反应条件
Lawesson's reagent
0.05 h; MW irradiation;
参考文献
Kiryanov; Sampson; Seed
Journal of Organic Chemistry, 2001 , vol. 66, # 23 p. 7925 - 7929
