4,5-二甲氧基-1H-吲哚合成路线 （共 6 条）
反应条件
silica gel; iron; acetic acid 1 h; Reflux;
参考文献
De Luca, Laura; De Grazia, Sara; Ferro, Stefania; Gitto, Rosaria; Christ, Frauke; Debyser, Zeger; Chimirri, Alba
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 756 - 764
反应条件
quinoline; copper Heating;
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
反应条件
1: 57 percent / methanol / -10 °C 2: 63 percent / xylene / Heating 3: 93 percent / aq. NaOH / Heating 4: 83 percent / Cu; quinoline / Heating View Scheme
参考文献
De Luca, Laura; De Grazia, Sara; Ferro, Stefania; Gitto, Rosaria; Christ, Frauke; Debyser, Zeger; Chimirri, Alba
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 756 - 764
反应条件
1: 93 percent / aq. NaOH / Heating 2: 83 percent / Cu; quinoline / Heating View Scheme
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
反应条件
1: ammonium acetate; acetic acid / 1.5 h / 118 °C 2: silica gel; iron; acetic acid / 1 h / Reflux View Scheme
参考文献
De Luca, Laura; De Grazia, Sara; Ferro, Stefania; Gitto, Rosaria; Christ, Frauke; Debyser, Zeger; Chimirri, Alba
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 756 - 764
反应条件
trichlorophosphate T=0 - 40°C; Vilsmeier formylation;
参考文献
Coowar, Djalil; Bouissac, Julien; Hanbali, Mazen; Paschaki, Marie; Mohier, Eliane; Luu, Bang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6270 - 6282
