反应条件
1.1: KOH; HOCH2CH2OH / H2O / Heating
1.2: AcOH / 0 °C
2.1: diethyl ether / 0 °C
3.1: LDA / tetrahydrofuran / -20 °C
3.2: 94 percent / hexamethylphosphoric acid triamide / -78 °C
4.1: AcOH / H2O / 25 - 60 °C
5.1: CrO3; aq. H2SO4 / acetone / 0 - 20 °C
6.1: diethyl ether / 0 °C
7.1: t-BuOK / benzene / Heating
8.1: DMSO; NaCl / 155 °C
9.1: N2H4; N2H4*HCl / bis-(2-hydroxy-ethyl) ether / 125 °C
9.2: KOH / bis-(2-hydroxy-ethyl) ether / 210 °C
View Scheme
参考文献
Gupta; Pal; Roy; Mukherjee
Tetrahedron Letters, 2000 , vol. 41, # 39 p. 7563 - 7566