1: 64 percent / aq. CAN / acetonitrile / 16 h / 20 °C 2: 189 mg / aq. HCl / diethyl ether / 16 h / 20 °C View Scheme

1: 64 percent / aq. CAN / acetonitrile / 16 h / 20 °C 2: 189 mg / aq. HCl / diethyl ether / 16 h / 20 °C View Scheme

1: 64 percent / aq. CAN / acetonitrile / 16 h / 20 °C 2: 189 mg / aq. HCl / diethyl ether / 16 h / 20 °C View Scheme

ammonium cerium(IV) nitrate in acetonitrile T=20°C; Hydrolysis; dealkylation;

<b>Multi-step reaction with 3 steps<br /> </b>1.1: NaBH₄ / ethanol / 0 - 20 &deg;C<br />2.1: BuLi / tetrahydrofuran / 0.5 h / -78 &deg;C<br />2.2: 77 percent / tetrahydrofuran / 2 h / -78 &deg;C<br />3.1: 89 percent / aq. CAN / acetonitrile / 16 h / 20 &deg;C<br /> <br /> &nbsp;