N-(2-boc-氨基乙基)-4-溴苯磺酰胺合成路线 (共 2 条)
反应条件
hydrogenchloride; sodium hydrogencarbonate; triethylamine; sodium chloride in dichloromethane; ethyl acetate
参考文献
Millennium Pharmaceuticals, Inc.
Patent: US6545055 B1, 2003 ;
US 6545055 B1
反应条件
1: (2-Amino-ethyl)-carbamic acid tert-butyl ester With triethylamine in dichloromethane 0.166667 h; 2: 4-bromobenzenesulfonyl chloride in dichloromethane T=20°C;
参考文献
GLAXO GROUP LIMITED
Patent: WO2008/34860 A1, 2008 ;
Location in patent: Page/Page column 132 ;
WO 2008/034860 A1