N-(4-羟基-3-甲氧基苄基)癸烷酰胺合成路线 （共 7 条）
反应条件
1: 3-methoxy-4-hydroxybenzylamine hydrochloride With sodium hydrogencarbonate in water T=20°C; 0.5 h; 2: n-decanoic acid chloride in chloroform; water T=20°C; 0.5 h;
参考文献
Wang, Bo; Yang, Fan; Shan, Yi-Fan; Qiu, Wen-Wei; Tang, Jie
Tetrahedron, 2009 , vol. 65, # 27 p. 5409 - 5412
反应条件
Streptomyces mobaraensis NBRC 13819 acylase in hexane T=37°C; pH=6.9; 96 h;
参考文献
Koreishi, Mayuko; Zhang, Demin; Imanaka, Hiroyuki; Imamura, Koreyoshi; Adachi, Shuji; Matsuno, Ryuichi; Nakanishi, Kazuhiro
Journal of Agricultural and Food Chemistry, 2006 , vol. 54, # 1 p. 72 - 78
反应条件
borate buffer; N-ethyl-N,N-diisopropylamine in water T=37°C; 48 h; pH = 9.0, chicken liver acetone powder (Sigma Chem. Co.);
参考文献
Kobata, Kenji; Yoshikawa, Koichi; Kohashi, Masahiro; Watanabe, Tatsuo
Tetrahedron Letters, 1996 , vol. 37, # 16 p. 2789 - 2790
反应条件
in diethyl ether; N,N-dimethyl-formamide Ambient temperature;
参考文献
Janusz, John M.; Buckwalter, Brian L.; Young, Patricia A.; LaHann, Thomas R.; Farmer, Ralph W.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 18 p. 2595 - 2604
反应条件
1: oxalyl chloride / 3 h 2: 69 percent / dimethylformamide; diethyl ether / Ambient temperature View Scheme
参考文献
Janusz, John M.; Buckwalter, Brian L.; Young, Patricia A.; LaHann, Thomas R.; Farmer, Ralph W.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 18 p. 2595 - 2604
参考文献
Nelson
Journal of the American Chemical Society, 1919 , vol. 41, p. 2121
Journal of the American Chemical Society, 1920 , vol. 42, p. 597
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in N,N-dimethyl-formamide T=20°C; 15 h;
参考文献
Cho, Yongsung; Kim, Myeong Seop; Kim, Ho Shin; Ann, Jihyae; Lee, Jeewoo; Lee, Jiyoun; Pearce, Larry V.; Pavlyukovets, Vladimir A.; Morgan, Matthew A.; Blumberg, Peter M.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 16 p. 5227 - 5231
