1-甲基-4-丙-2-烯基磺酰基苯合成路线 （共 91 条）
反应条件
1-hydroxy-2(1H)-pyridinethione; 4-(N,N-dimethlyamino)pyridine in toluene
T=110°C; 2 h;
参考文献
Barton, Derek H. R.; Crich, David
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1613 - 1620
反应条件
n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h;
参考文献
Hiroi, Kunio; Kitayama, Ryuichi; Sato, Shuko
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 7 p. 2628 - 2638
反应条件
n-butyllithium in tetrahydrofuran; hexane
1) -78 deg C, 2) -30 deg C, 30 min;
参考文献
Julia, Marc; Righini-Tapie, Anne; Verpeaux, Jean-Noel
Tetrahedron, 1983 , vol. 39, # 20 p. 3283 - 3288
反应条件
lithium bromide
1.) THF-ether, -70 deg C, 30 min; 2.) -70 deg C, 135 min; Yield given. Multistep reaction;
参考文献
Knight, Derek J.; Lin, Peter; Russell, Simon T.; Whitham, Gordon H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2701 - 2706
反应条件
n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h;
参考文献
Hiroi, Kunio; Kitayama, Ryuichi; Sato, Shuko
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 7 p. 2628 - 2638
反应条件
1: BF3; H2SO4 / 105 °C
2: LiAlH4; diethyl ether
View Scheme
参考文献
Karaulowa et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 662,665; engl. Ausg. S. 655, 657
反应条件
dichloro bis(acetonitrile) palladium(II); oxygen; copper dichloride in tetrahydrofuran
T=25°C; P=760 Torr; 120 h; Yield given. Yields of byproduct given;
参考文献
Toda, Shiho; Miyamoto, Masanori; Kinoshita, Hideki; Inomata, Katsuhiko
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 12 p. 3600 - 3606
反应条件
1: 92 percent / PdCl2, Cu(OAc)2, NaCl / acetic acid; acetic anhydride / 48 h / 60 °C
2: 92 percent / conc. HCl / methanol / 48 h / Ambient temperature
View Scheme
参考文献
Najera, Carmen; Yus, Miguel
Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1491 - 1499
反应条件
oxygen; p-benozquinone; copper(I) bromide dimethylsulfide complex; copper(l) chloride; palladium dichloride in water; N,N-dimethyl-formamide
P=750.06 Torr; 20 h; Ambient temperature; Product distribution;
参考文献
Muzart, Jacques; Pete, Jean-Pierre; Riahi, Abdelkhalek
Journal of Organometallic Chemistry, 1987 , vol. 331, # 1 p. 113 - 120
反应条件
oxygen; palladium (II) trifluoroacetate; cupric trifluoroacetate in acetone
160 h; Ambient temperatureIrradiationstudy of the Pd(OCOCH3)2 catalyzed regioselective oxidation reaction of various allyl sulfones; Product distribution;
参考文献
Muzart, J.; Riahi, A.; Pete, J. P.
Journal of Organometallic Chemistry, 1985 , vol. 280, p. 269 - 280
