5-甲基-2-硝基苯甲酸合成路线 （共 50 条）
参考文献
Chemische Berichte, , vol. 47, p. 408
参考文献
Journal of the Chemical Society, , p. 2067,2070
参考文献
Gazzetta Chimica Italiana, , vol. 65, p. 840,842
参考文献
Monatshefte fuer Chemie, , vol. 41, p. 155
反应条件
1: potassium tert-butylate / ethanol / 20 °C 2: oxygen; copper diacetate; silver carbonate / N,N-dimethyl-formamide / 18 h / 145 °C View Scheme
参考文献
Bhadra, Sukalyan; Dzik, Wojciech I.; Goossen, Lukas J.
Journal of the American Chemical Society, 2012 , vol. 134, # 24 p. 9938 - 9941
反应条件
1: dimethylsulfide borane complex / tetrahydrofuran / 3 h / 80 °C / |Inert atmosphere 2: phosphorus tribromide / diethyl ether / 3 h / |Inert atmosphere View Scheme
参考文献
UNIVERSITY OF UTAH RESEARCH FOUNDATION; JI, Haitao; YU, Binxun; ZHANG, Min; GUO, Wenxing
Patent: WO2013/120045 A1, 2013 ;
反应条件
1: 91 percent / conc. H2SO4 / 48 h / Heating 2: 31 percent / CF3SO3H, fuming HNO3 / CH2Cl2 / 20 h / 25 °C 3: 70 percent / dimethylformamide / 4 h / 100 °C 4: 48 percent / H2 / Pd/C / methanol / 4 h / 2585.7 Torr View Scheme
参考文献
Showalter, H. D. Hollis; Sun, Li; Sercel, Anthony D.; Winters, R. Thomas; Denny, William A.; Palmer, Brian D.
Journal of Organic Chemistry, 1996 , vol. 61, # 3 p. 1155 - 1158
反应条件
ammonia; palladium monocarbide in tetrahydrofuran; methanol; N,N-dimethyl-formamide
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5389641 A1, 1995 ;
US 5389641 A
反应条件
1: 1.) SOCl2, 2.) NaOH, NH4OH / 1.) reflux, 20 min, 2.) THF 2: 96 percent / H2 / 5percent Pd/C / methanol / 24 h / 2280 Torr View Scheme
参考文献
Raffa, Demetrio; Maggio, Benedetta; Raimondi, Maria Valeria; Cusimano, Maria Grazia; Amico, Giandomenico; Carollo, Anna; Conaldi, Pier Giulio; Bai, Ruoli; Hamel, Ernest; Daidone, Giuseppe
European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 427 - 435
反应条件
triphenylphosphine; silver carbonate; palladium dichloride in dimethyl sulfoxide T=130°C; 6 h; Inert atmosphere;
参考文献
Xie, Kai; Wang, Sizhuo; Yang, Zhiyong; Liu, Jidan; Wang, Anwei; Li, Xiujian; Tan, Ze; Guo, Can-Cheng; Deng, Wei
European Journal of Organic Chemistry, 2011 , # 29 p. 5787 - 5790
