2-溴-5-苯甲酰基噻吩合成路线 (共 13 条)
反应条件
1: C10H13BrMgO With bismuth(III) chloride
2: 2-benzoyl-5-bromothiophene With potassium phosphate; palladium diacetate; triphenylphosphine in N,N-dimethyl-formamide
T=90°C; 1 h; Inert atmosphere;
参考文献
Rao, Maddali L. N.; Banerjee, Debasis; Dhanorkar, Ritesh J.
Synlett, 2011 , # 9 p. 1324 - 1330
参考文献
Pfizer Inc.
Patent: US4282246 A1, 1981 ;
反应条件
1: m-trifluoro-methyl-phenyl-magnesium bromide With bismuth(III) chloride
2: 2-benzoyl-5-bromothiophene With potassium phosphate; palladium diacetate; triphenylphosphine in N,N-dimethyl-formamide
T=90°C; 1 h; Inert atmosphere;
参考文献
Rao, Maddali L. N.; Banerjee, Debasis; Dhanorkar, Ritesh J.
Synlett, 2011 , # 9 p. 1324 - 1330