2,3-二甲氧基-1,4-苯醌合成路线 （共 30 条）
反应条件
1: 98 percent / H2 / 10percent Pd-C / acetic acid / 0.5 h 2: 78 percent / K2(SO3)2NO, aq. NaOAc / benzene View Scheme
参考文献
Synthesis, , # 6/7 p. 626 - 631
反应条件
1: p-toluenesulfonic acid, H2O / methanol / 8 h / Ambient temperature 2: 100 percent / K2CO3 / acetone / 1 h / Heating 3: 98 percent / H2 / 10percent Pd-C / acetic acid / 0.5 h 4: 78 percent / K2(SO3)2NO, aq. NaOAc / benzene View Scheme
参考文献
Synthesis, , # 6/7 p. 626 - 631
反应条件
1: 77 percent / ion-exchange resin Amberlyst 15 / benzene / 10 h / Heating 2: 90 percent / NaOH / dioxane / 14 h / 100 °C 3: p-toluenesulfonic acid, H2O / methanol / 8 h / Ambient temperature 4: 100 percent / K2CO3 / acetone / 1 h / Heating 5: 98 percent / H2 / 10percent Pd-C / acetic acid / 0.5 h 6: 78 percent / K2(SO3)2NO, aq. NaOAc / benzene View Scheme
参考文献
Synthesis, , # 6/7 p. 626 - 631
反应条件
dihydrogen peroxide in formic acid; water T=40°C; 2 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 5 p. 1652 - 1657
反应条件
1: 1.) m-chloroperbenzoic acid, 2.) sodium thiosulfate / 1.) methylene chloride, 2 h, r.t., 2.) water, 45 min 2: 0.8 g / ceric ammonium nitrate / acetonitrile; H2O / 0.25 h View Scheme
参考文献
Acta Chimica Hungarica, , vol. 120, # 2 p. 163 - 166
反应条件
in chloroform-d1 T=25.9°C; activation energie (Ea), other temperatures; Rate constantThermodynamic data;
参考文献
Journal of Organic Chemistry, , vol. 50, # 7 p. 1106 - 1107
反应条件
in chloroform Oxidation; 3 h; Heating; Further byproducts given;
参考文献
Journal of Chemical Research, Miniprint, , # 8 p. 2001 - 2019
反应条件
1: benzene / 35 h / Ambient temperature 2: 93 percent / pyridine / Ambient temperature View Scheme
参考文献
Flynn; Nies
Tetrahedron Letters, 1986 , vol. 27, # 42 p. 5075 - 5078
反应条件
1: BF3-Et2O 2: aq. HCl / methanol / Heating 3: (i) Ag2O, Et2O, (ii) /BRN= 102415/ View Scheme
参考文献
Catlin,J.C. et al.
Journal of Medicinal Chemistry, 1971 , vol. 14, # 1 p. 45 - 48
反应条件
1: in ethanol; hexane
2: With Fremy’s salt; sodium acetate in methanol
参考文献
Mori, Koichi; Ushio, Tomoe; Okamoto, Tadashi; Kishi, Takeo; Sayo, Hiroteru
Biological & Pharmaceutical Bulletin, 1998 , vol. 21, # 3 p. 293 - 296
