2,3-二甲氧基-1,4-苯醌合成路线 (共 30 条)
参考文献
Folkers,K. et al.
Journal of Medicinal Chemistry, 1974 , vol. 17, p. 893 - 896
参考文献
Birkofer, Leonhard; Foremny, Vera
Zeitschrift fuer Chemie (Stuttgart, Germany), 1983 , vol. 23, # 7 p. 250
反应条件
1: benzene / 35 h / Ambient temperature
2: 93 percent / pyridine / Ambient temperature
3: d,l-camphorsulfonic acid / CH2Cl2
View Scheme
参考文献
Flynn; Nies
Tetrahedron Letters, 1986 , vol. 27, # 42 p. 5075 - 5078
反应条件
1: in ethanol; hexane
2: With Fremy’s salt; sodium acetate in methanol
参考文献
Mori, Koichi; Ushio, Tomoe; Okamoto, Tadashi; Kishi, Takeo; Sayo, Hiroteru
Biological & Pharmaceutical Bulletin, 1998 , vol. 21, # 3 p. 293 - 296
参考文献
Folkers,K. et al.
Journal of Medicinal Chemistry, 1974 , vol. 17, p. 893 - 896
反应条件
2: (i) HCl, (ii) NO2
View Scheme
参考文献
Folkers,K. et al.
Journal of Medicinal Chemistry, 1974 , vol. 17, p. 893 - 896
参考文献
Folkers,K. et al.
Journal of Medicinal Chemistry, 1974 , vol. 17, p. 893 - 896
反应条件
1: in ethanol; hexane
2: With Fremy’s salt; sodium acetate in methanol
参考文献
Mori, Koichi; Ushio, Tomoe; Okamoto, Tadashi; Kishi, Takeo; Sayo, Hiroteru
Biological & Pharmaceutical Bulletin, 1998 , vol. 21, # 3 p. 293 - 296
反应条件
anhydrous sulfurous acid
参考文献
Weygand et al.
Chemische Berichte, 1957 , vol. 90, p. 1879,1890
参考文献
Astrazeneca AB
Patent: US6472435 B1, 2002 ;
US 6472435 B1