N-(6-氯吡啶-3-甲基)吗啉合成路线 （共 3 条）
反应条件
in tetrachloromethane T=20°C; 6 h;
参考文献
F2G LTD
Patent: WO2008/62182 A1, 2008 ;
Location in patent: Page/Page column 144 ;
参考文献
Maienfisch, Peter; Haettenschwiler, Joerg; Rindlisbacher, Alfred; Decock, Arnaud; Wellmann, Henning; Kayser, Hartmut
Chimia, 2003 , vol. 57, # 11 p. 710 - 714
反应条件
1: 2-oxo-2,3-dihydro-indole-5-carbonitrile With sodium hydride in N,N-dimethyl-formamide
0.25 h;
2: N-(6-chloropyridin-3-ylmethyl)morpholine in N,N-dimethyl-formamide
1 h; Heating / reflux; Product distribution / selectivity;
参考文献
ASTRAZENECA AB
Patent: WO2003/82853 A1, 2003 ;
Location in patent: Page/Page column 59 ;
WO 03/082853 A1
