in acetic anhydride

1 h; Heating;

1: 81 percent / m-chlorperbenzoic acid / CH2Cl2 / 24 h / Ambient temperature 2: 67 percent / 8 h / 120 °C 3: 67 percent / Amberlite CC 120 I, (H+) / ethanol; H2O / 18 h / Heating View Scheme

1: 89 percent / 45percent HBr / acetic acid / 3 h / Heating 2: 59 percent / Na / ethanol; tetrahydrofuran / 18 h / Heating 3: 1.) 6M NaOH / 1.) EtOH, room temperature, 1.5 h, 2.) dioxane, reflux, 1.5 h 4: 36 percent / α-chymotrypsin, NH4OAc, pH 6.9, 1 M NH4OH / dimethylformamide; H2O / 2 h / Ambient temperature 5: 85 percent / 5M HCl / 3.5 h / Heating View Scheme

hydrogenchloride 24 h; Heating;