2-[(2-氯-4-嘧啶)氨基]-苯甲酸合成路线 （共 3 条）
反应条件
hydrogenchloride T=20 - 50°C;
参考文献
Liu, Mei; Wang, Sanyi; Clampit, Jill E.; Gum, Rebecca J.; Haasch, Deanna L.; Rondinone, Cristina M.; Trevillyan, James M.; Abad-Zapatero, Cele; Fry, Elizabeth H.; Sham, Hing L.; Liu, Gang
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 668 - 672
反应条件
sodium in methanol
T=110°C; 6 h;
参考文献
Karn, V. K.; Tat'yanchenko, I. S.; Portnyagina, V. A.; Mokhort, N. A.; Ryabukha, T. K.; Vinnikova, A. V.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 777 - 779
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1304 - 1307
反应条件
hydrazine hydrate in methanol
3 h; Heating;
参考文献
Karn, V. K.; Tat'yanchenko, I. S.; Portnyagina, V. A.; Mokhort, N. A.; Ryabukha, T. K.; Vinnikova, A. V.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 11 p. 777 - 779
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 11 p. 1304 - 1307
