2-(三氟甲基)苯并咪唑合成路线 (共 35 条)
反应条件
tris(trimethylsilyl)silyl chloride in acetonitrile T=80°C; 48 h; Inert atmosphere;
参考文献
Wiehn, Matthias S.; Vinogradova, Ekaterina V.; Togni, Antonio
Journal of Fluorine Chemistry, 2010 , vol. 131, # 9 p. 951 - 957
反应条件
toluene-4-sulfonic acid in toluene Heating;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 104, # 12 p. 707 - 716
反应条件
in methanol 168 h; Ambient temperatureIrradiation; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 47, # 15 p. 2867 - 2872
反应条件
1: in N,N-dimethyl acetamide T=100°C; 1.5 h; 2: With water in N,N-dimethyl acetamide cooling;
参考文献
Russian Journal of Organic Chemistry, , vol. 42, # 4 p. 558 - 566
反应条件
in chloroform T=20°C; 20 h;
参考文献
Kamitori
Tetrahedron Letters, 2000 , vol. 41, # 48 p. 9267 - 9270
反应条件
in dichloromethane 3 h;
参考文献
Rover-Kevers, Monique; Vertommen, Luc; Huys, Fabienne; Merenyi, Robert; Janousek, Zdenek; Viehe, Heinz Guenther
Angewandte Chemie, 1981 , vol. 93, # 12 p. 1091 - 1092
反应条件
in xylene 30 h; Heating;
参考文献
Journal of Fluorine Chemistry, , vol. 125, # 9 p. 1363 - 1370
反应条件
in N,N-dimethyl acetamide T=100°C; 1.5 h; Title compound not separated from byproducts;
参考文献
Russian Journal of Organic Chemistry, , vol. 42, # 4 p. 558 - 566
反应条件
in N,N-dimethyl acetamide 1.5 h; Heating;
参考文献
Journal of Fluorine Chemistry, , vol. 126, # 6 p. 976 - 983
反应条件
hydrogenchloride; nitric acid in water T=60°C; 28 h; Reflux;
参考文献
Laudy, Agnieszka E.; Moo-Puc, Rosa; Cedillo-Rivera, Roberto; Kazimierczuk, Zygmunt; Orzeszko, Andrzej
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 5 p. 1059 - 1065