(5alpha)-17,21-二羟基孕甾烷e-3,20-二酮合成路线 （共 9 条）
反应条件
potassium hydroxide in methanol 1 h;
参考文献
Gerasimova, M. L.; Gusarova, T. I.; Ryzhkova, V. M.; Bykova, T. M.; Alekseeva, L. M.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 10 p. 863 - 868
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 10 p. 1259 - 1263
反应条件
2: (N,N-dimethylamino)pyridine, pyridine 3: 92 percent / PdCl2(CH3CN)2 / tetrahydrofuran / Ambient temperature 4: 1. KOH, 2.) N-bromoacetamide View Scheme
参考文献
Murahashi, Shun-Ichi; Saito, Takao; Hanaoka, Hidenori; Murakami, Yoshihide; Naota, Takeshi; et al.
Journal of Organic Chemistry, 1993 , vol. 58, # 11 p. 2929 - 2930
反应条件
1: 92 percent / PdCl2(CH3CN)2 / tetrahydrofuran / Ambient temperature 2: 1. KOH, 2.) N-bromoacetamide View Scheme
参考文献
Murahashi, Shun-Ichi; Saito, Takao; Hanaoka, Hidenori; Murakami, Yoshihide; Naota, Takeshi; et al.
Journal of Organic Chemistry, 1993 , vol. 58, # 11 p. 2929 - 2930
反应条件
in ethanol T=24 - 26°C; 96 h; Penicillium decumbens ATCC 10436, potato dextrose broth;
参考文献
Holland, Herbert L.
Steroids, 1995 , vol. 60, # 9 p. 646 - 649
反应条件
in ethanol T=24 - 26°C; 96 h; Penicillium decumbens ATCC 10436, potato dextrose broth;
参考文献
Holland, Herbert L.
Steroids, 1995 , vol. 60, # 9 p. 646 - 649
反应条件
1: H2 / 5percent Pd-C / ethanol; ethyl acetate / 14 h 2: 2N HCl / H2O 3: NaOH / methanol; dioxane View Scheme
参考文献
Hosoda; Takasaki; Miura; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 10 p. 4281 - 4287
反应条件
potassium hydroxide; N-bromoacetamide
参考文献
Murahashi, Shun-Ichi; Saito, Takao; Hanaoka, Hidenori; Murakami, Yoshihide; Naota, Takeshi; et al.
Journal of Organic Chemistry, 1993 , vol. 58, # 11 p. 2929 - 2930
反应条件
mit Hilfe von homogenisierter Rattenleber;
参考文献
Forchielli et al.
Journal of Biological Chemistry, 1955 , vol. 215, p. 713,717
参考文献
Murahashi, Shun-Ichi; Saito, Takao; Hanaoka, Hidenori; Murakami, Yoshihide; Naota, Takeshi; et al.
Journal of Organic Chemistry, 1993 , vol. 58, # 11 p. 2929 - 2930
