5-甲基四氢吡喃-2-酮合成路线 （共 17 条）
反应条件
1: 90 percent / aq, HCl / 1 h / Heating 2: 80 percent / sodium borohydride / methanol / 0.5 h / 20 °C 3: 91 percent / aq. sodium hydroxide / methanol / 2.5 h / Heating View Scheme
参考文献
Archibald, Sarah C.; Barden, David J.; Bazin, Jerome F.Y.; Fleming, Ian; Foster, Colin F.; Mandal, Ajay K.; Mandal, Amit K.; Parker, David; Takaki, Ken; Ware, Anne C.; Williams, Anne R.B.; Zwicky, Anna B.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 7 p. 1051 - 1064
反应条件
1: 94 percent / NaBH4 / methanol / 1.5 h / Ambient temperature 2: KOH / H2O / 3 h / Heating 3: conc. H2SO4 / H2O / 3 h / Heating View Scheme
参考文献
Tokoroyama, Takashi; Kusaka, Hisashi
Canadian Journal of Chemistry, 1996 , vol. 74, # 12 p. 2487 - 2502
反应条件
1: KOH / H2O / 3 h / Heating 2: conc. H2SO4 / H2O / 3 h / Heating View Scheme
参考文献
Tokoroyama, Takashi; Kusaka, Hisashi
Canadian Journal of Chemistry, 1996 , vol. 74, # 12 p. 2487 - 2502
反应条件
1: dimethylsulfide; ozone / dichloromethane / -78 °C 2: pyridine; palladium diacetate / toluene / 80 °C / Molecular sieve View Scheme
参考文献
Takeda, Kazutaka; Toyota, Masahiro
Tetrahedron Letters, 2011 , vol. 52, # 44 p. 5872 - 5875
反应条件
1: sodium tetrahydroborate / ethanol / 0 °C 2: dimethylsulfide; ozone / dichloromethane / -78 °C 3: pyridine; palladium diacetate / toluene / 80 °C / Molecular sieve View Scheme
参考文献
Takeda, Kazutaka; Toyota, Masahiro
Tetrahedron Letters, 2011 , vol. 52, # 44 p. 5872 - 5875
反应条件
1: aq. HCl 2: KBH4 View Scheme
参考文献
Ficini,J.; Krief,A.
Tetrahedron Letters, 1970 , p. 885 - 888
参考文献
Ube Industries, Ltd.
Patent: US3953514 A1, 1976 ;
