1-甲氧基-4-(2-硝基乙基)苯合成路线 (共 14 条)
反应条件
Yield given. Multistep reaction;
参考文献
Urpi, Feelix; Vilarrasa, Jaume
Tetrahedron Letters, 1990 , vol. 31, # 51 p. 7499 - 7500
反应条件
samarium diiodide; water; isopropylamine in tetrahydrofuran
参考文献
Ankner, Tobias; Hilmersson, Goeran
Tetrahedron Letters, 2007 , vol. 48, # 32 p. 5707 - 5710
反应条件
4-(N,N-dimethlyamino)pyridine; Sn(thiophenolate)4; tributylphosphine; diethylazodicarboxylate in dichloromethane T=0°C; 0.0833333 h;
参考文献
Tetrahedron Letters, , vol. 31, # 51 p. 7497 - 7498
反应条件
1: 65 percent / dimethylamine hydrochloride, KF / toluene / Heating
2: 70 percent / silica, NaBH4 / propan-2-ol; CHCl3 / 0.25 h / 25 °C
3: 60 percent / aq. chromous chloride / tetrahydrofuran / 0.17 h / Ambient temperature
View Scheme
参考文献
McNamara, Yvonne M.; Cloonan, Suzanne M.; Knox, Andrew J.S.; Keating, John J.; Butler, Stephen G.; Peters, Guenther H.; Meegan, Mary J.; Williams, D. Clive
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 3 p. 1328 - 1348